When IVF provides many embryos, it is legitimate to expect J3 before relocating to select the best, or to push the culture of blastocysts to transfer the highest quality.
But if the embryos are few and do not warrant a selection, a study in “Fertility & Sterility” May states that the transfer to J2 regardless of embryo quality increases the chances of pregnancy in women under 40 years.
It establishes and “the date of transfer is a significant predictor of clinical outcome in cases where a small number of embryos available for transfer. Evidence suggests that limiting embryo culture only 2 days reduces the miscarriage and increases the pregnancy rate continued.”
This study echoes another issued in 2004 which had focused on the results of 2027 women. It was shown that transfer to D3 increased the clinical pregnancy rate in ICSI cycles but that the rate of miscarriage is not possible to increase correspondingly the rate of live births.
The extracts (English)
“Day 2 transfer improves pregnancy outcome in in vitro fertilization cycles with few available embryos.” by Shen s , Rosen MP, Dobson AT, Fujimoto VY, McCulloch CE, Cedars MI. Fertility & Sterility, 2006. doi:10.1016/j.fertnstert.2005.12.020
Oatway C, Gunby J, Daya S. Day three versus day two embryo transfer following in vitro fertilization or intracytoplasmic sperm injection. The Cochrane Database of Systematic Reviews 2004, Issue 2. Type. No.: CD004378. DOI: 10.1002/14651858.CD004378.pub2.
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