Several recent studies have compared the performance of Menopur and Gonal-F in vitro fertilization.
The objective was to observe if women who have undergone stimulation are more likely to achieve pregnancy with the evolutionary Ménopur, when it is already established that the Gonal-F induces greater production of eggs.
Two studies published in 2004 had legitimized the issue. A large study, randomized 731 women, Print this objective.
Sponsored by the manufacturer of Menopur, Ferring Laboratory, this study named “Merit” has established that ovarian stimulation with Menopur conducted
induced in 27% cases against the group 22% cases the group Gonal-F (insignificant difference).
But above all systematic photography of embryos (oocyte stages, J2 and J3) was used to assess the quality of embryos obtained. And especially, rate
ongoing pregnancy (jusqu'à S11)of these embryos is high quality 48% Menopur and under 32% as Gonal-F.
The Gonal-F (r-FSH) has an estrogenic action, while the simple menotropin Menopur induces an action of FSH and LH (hormone lutéinique), closer to the action
- 1/ www.prnewswire.co.uk/cgi/news/release?id=122803
- 2/ www.prnewswire.co.uk/cgi/news/release?id=125754
- 3/ Article summary “Embryo quality in Menopur“, in “gp”, N°2342, September 2005
- 4/ All about sex hormones
- 5/ “the drugs fertility drugs, guidelines of good practices“,
AFSSAPS 2004, summary table and p20 following (Pdf document.)
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